null

SMILES CCOC(=O)C(C#N)C1C(C(=O)OCC)C(=N)Oc2ccc(Br)cc12

InChI Key InChIKey=DMETXMZYCSYQHI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50200965   

TargetBcl-2-like protein 2(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50200965(2-Amino-6-bromo-4-(cyano-ethoxycarbonyl-methyl)-4H...)copy SMILEScopy InChI
Affinity DataKi:  2.10E+5nMAssay Description:Displacement of Flu-Bak peptide from recombinant antiapoptopic Bcl-w protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3F4CPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50200965(2-Amino-6-bromo-4-(cyano-ethoxycarbonyl-methyl)-4H...)copy SMILEScopy InChI
Affinity DataKi:  2.54E+5nMAssay Description:Displacement of Flu-Bak peptide from recombinant antiapoptopic Bcl2 protein by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3F4CPubMed
TargetBcl-2-like protein 1(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50200965(2-Amino-6-bromo-4-(cyano-ethoxycarbonyl-methyl)-4H...)copy SMILEScopy InChI
Affinity DataKi:  6.60E+5nMAssay Description:Inhibition of recombinant His6-tagged Bcl-XL expressed in Escherichia coli BL21 (DE3) and Flu-Bak peptide interaction by fluorescence polarization as...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28053JDPubMed
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50200965(2-Amino-6-bromo-4-(cyano-ethoxycarbonyl-methyl)-4H...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails