null

SMILES COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1ccc2nccc(-c3ccc(CN(C)CCO)cc3)c2c1

InChI Key InChIKey=WKECSELYDBZHQV-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50202550   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50202550(CHEMBL3905146)copy SMILEScopy InChI
Affinity DataIC50: 0.590nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD71FDPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50202550(CHEMBL3905146)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD71FDPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50202550(CHEMBL3905146)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by ADP-glo based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD71FDPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50202550(CHEMBL3905146)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate after 1 hr in presence of ATP by ADP-glo based luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD71FDPubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50202550(CHEMBL3905146)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Inhibition of mTOR (unknown origin) using ULight-4E-BP1 peptide as substrate after 1 hr in presence of ATP by lance ultra assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD71FDPubMed