null
SMILES COc1cccc2c1[nH]c1c2c(cc2cnccc12)C#N
InChI Key InChIKey=UHOPJKMQVDXYAV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50208625
Affinity DataIC50: 44nMAssay Description:Inhibition of GST-tagged human recombinant CLK2 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
CNRS
Curated by ChEMBL
CNRS
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of GST-tagged human recombinant DYRK1B expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [g...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of GST-tagged human recombinant CLK4 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
CNRS
Curated by ChEMBL
CNRS
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of GST-tagged human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [g...More data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of GST-tagged human recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...More data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 460nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrate after 30 mins in presence of [gamma-33 P] ATP by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails
In DepthDetails
In DepthDetails
Affinity DataIC50: 180nMAssay Description:Inhibition of GST-tagged human recombinant CLK3 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...More data for this Ligand-Target Pair