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SMILES Cc1cccc2[nH]c(nc12)-c1c(NCC(O)c2cccc(Cl)c2)cc[nH]c1=O

InChI Key InChIKey=LOYHRPQPVDZCBA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50209378   

TargetCytochrome P450 1A2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209378(4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-3-(4-me...)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibition of CYP1A2 in microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76C71PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209378(4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-3-(4-me...)copy SMILEScopy InChI
Affinity DataIC50: 710nMAssay Description:Inhibition of CYP3A4 in microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76C71PubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209378(4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-3-(4-me...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of CYP2C9 in microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76C71PubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209378(4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-3-(4-me...)copy SMILEScopy InChI
Affinity DataIC50: 770nMAssay Description:Inhibition of human IGF1R expressed in recombinant insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76C71PubMed