null

SMILES CNC(=O)c1cc(C)c2nc([nH]c2c1)-c1c(NCC(O)c2cccc(Cl)c2)cc[nH]c1=O

InChI Key InChIKey=VNHSWSVUHFYHIZ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50209386   

TargetCytochrome P450 2C9(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209386(2-(4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-2-ox...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of CYP2C9 in microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76C71PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209386(2-(4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-2-ox...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of CYP1A2 in microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76C71PubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209386(2-(4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-2-ox...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of human IGF1R expressed in recombinant insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76C71PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209386(2-(4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-2-ox...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of CYP3A4 in microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76C71PubMed