null

SMILES Fc1ccc(cc1)[C@@H](CC(=O)N[C@@H]1CCOc2cc(CN3CCCCC3)ccc12)NS(=O)(=O)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=DRRWMFNQXRLTHS-VSGBNLITSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50209744   

TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50209744((R)-3-(4-fluorophenyl)-N-((R)-7-(piperidin-1-ylmet...)copy SMILEScopy InChI
Affinity DataKi:  0.400nMAssay Description:Antagonist activity at human bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79R6PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50209744((R)-3-(4-fluorophenyl)-N-((R)-7-(piperidin-1-ylmet...)copy SMILEScopy InChI
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]DAK from human bradykinin B1 receptor expressed in CHOD cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3SG2PubMed
TargetB1 bradykinin receptor(RAT)
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50209744((R)-3-(4-fluorophenyl)-N-((R)-7-(piperidin-1-ylmet...)copy SMILEScopy InChI
Affinity DataKi:  127nMAssay Description:Antagonist activity at rat bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3SG2PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50209744((R)-3-(4-fluorophenyl)-N-((R)-7-(piperidin-1-ylmet...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in CHO cells assessed as inhibition of agonist-induced calcium efflux by aquerin based ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79R6PubMed
TargetB1 bradykinin receptor(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50209744((R)-3-(4-fluorophenyl)-N-((R)-7-(piperidin-1-ylmet...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Antagonist activity at human bradykinin B1 receptor expressed in CHOD cellsassessed as effect on DAK-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3SG2PubMed
TargetB1 bradykinin receptor(Oryctolagus cuniculus)
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50209744((R)-3-(4-fluorophenyl)-N-((R)-7-(piperidin-1-ylmet...)copy SMILEScopy InChI
Affinity DataIC50: 10.4nMAssay Description:Antagonist activity at rabbit bradykinin B1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3SG2PubMed