null

SMILES CN1CCN(Cc2ccc-3c(Cc4c-3n[nH]c4-c3csc(c3)C#CCOc3ccccc3)c2)CC1

InChI Key InChIKey=JPKSISIJPSXDLA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50210272   

TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210272(6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of PDGFR by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16K0PubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210272(6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of Flt4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16K0PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210272(6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16K0PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210272(6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of CSF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16K0PubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210272(6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of Flt1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16K0PubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210272(6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16K0PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210272(6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 3.04E+4nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16K0PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210272(6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of c-KitMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16K0PubMed
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210272(6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of HckMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16K0PubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210272(6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16K0PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210272(6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16K0PubMed
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210272(6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 2.73E+4nMAssay Description:Inhibition of FynMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16K0PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210272(6-((4-methylpiperazin-1-yl)methyl)-3-(5-(3-phenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of Flt3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16K0PubMed