null

SMILES CN(C)C(=O)COc1ccc-2c(Cc3c-2n[nH]c3-c2csc(c2)C#CCOc2ccccc2)c1

InChI Key InChIKey=JXRNOMQKAQYKAL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50210284   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210284(CHEMBL374690 | N,N-dimethyl-2-(3-(5-(3-phenoxyprop...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16K0PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210284(CHEMBL374690 | N,N-dimethyl-2-(3-(5-(3-phenoxyprop...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of hERG expressed in HEK293 cells assessed as effect on ionic current by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16K0PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210284(CHEMBL374690 | N,N-dimethyl-2-(3-(5-(3-phenoxyprop...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16K0PubMed