null

SMILES COCCOCC#Cc1cc(cs1)-c1[nH]nc2-c3ccc(CN4CCN(C)CC4)cc3C(=O)c12

InChI Key InChIKey=YACXOXQTGJXYNX-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50210296   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210296(3-(5-(3-(2-methoxyethoxy)prop-1-ynyl)thiophen-3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 9.40E+3nMAssay Description:Displacement of [3H]dofetilide from hERG expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16K0PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210296(3-(5-(3-(2-methoxyethoxy)prop-1-ynyl)thiophen-3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of hERG expressed in HEK293 cells assessed as effect on ionic current by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16K0PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210296(3-(5-(3-(2-methoxyethoxy)prop-1-ynyl)thiophen-3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16K0PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210296(3-(5-(3-(2-methoxyethoxy)prop-1-ynyl)thiophen-3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human KDRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16K0PubMed