null

SMILES COCCOCC#Cc1cc(cs1)-c1[nH]nc-2c1Cc1ccc(CN3CCN(C)CC3)cc-21

InChI Key InChIKey=BFOAUCMLYYUSJH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50210297   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210297(3-(5-(3-(2-methoxyethoxy)prop-1-ynyl)thiophen-3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16K0PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210297(3-(5-(3-(2-methoxyethoxy)prop-1-ynyl)thiophen-3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of hERG expressed in HEK293 cells assessed as effect on ionic current by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16K0PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50210297(3-(5-(3-(2-methoxyethoxy)prop-1-ynyl)thiophen-3-yl...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of VEGF-induced phosphorylation of human KDR expressed in mouse NIH3T3 cell line by Western blotMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB16K0PubMed