null

SMILES CC1C2CCC3(C)Cc4sc(NC(=O)Nc5ccc(F)cc5F)nc4C(C)C3C2OC1=O

InChI Key InChIKey=GVJPHCMMJLXNDI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50211482   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211482(1-(2,4-difluoro-phenyl)-3-(3,5a,10-trimethyl-2-oxo...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of partially purified human 5-LO expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Johann Wolfgang Goethe-Universität

Curated by ChEMBL
LigandPNGBDBM50211482(1-(2,4-difluoro-phenyl)-3-(3,5a,10-trimethyl-2-oxo...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of 5-LO activity in ionophore A23187 and arachidonic-stimulated human intact PMNLMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80T8PubMed