null

SMILES CNC(=O)Nc1ccc(CNc2c(cnn2C)C(=O)Nc2ccc3OC(F)(F)C(F)(F)Oc3c2)cn1

InChI Key InChIKey=MEQSMKIFBMBPQX-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50215768   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215768(1-methyl-3-(5-((1-methyl-4-((2,2,3,3-tetrafluoro-2...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K78S7PubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215768(1-methyl-3-(5-((1-methyl-4-((2,2,3,3-tetrafluoro-2...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K78S7PubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215768(1-methyl-3-(5-((1-methyl-4-((2,2,3,3-tetrafluoro-2...)copy SMILEScopy InChI
Affinity DataIC50: 448nMAssay Description:Inhibition of P-ERKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K78S7PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215768(1-methyl-3-(5-((1-methyl-4-((2,2,3,3-tetrafluoro-2...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of pAktMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K78S7PubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215768(1-methyl-3-(5-((1-methyl-4-((2,2,3,3-tetrafluoro-2...)copy SMILEScopy InChI
Affinity DataIC50: 191nMAssay Description:Inhibition of b-RafMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K78S7PubMed