null

SMILES CC(C)C1CC[C@@H](NC(=O)N2CCC(CC2)n2c3cccnc3[nH]c2=O)C(=O)NC1

InChI Key InChIKey=VEHSPEHQVKZXJV-BZSJEYESSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50224428   

TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50224428(CHEMBL240904 | N-[(3R)-6-isopropyl-2-oxoazepan-3-y...)copy SMILEScopy InChI
Affinity DataKi:  470nMAssay Description:Displacement of [125I]CGPR from human CL receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W02PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50224428(CHEMBL240904 | N-[(3R)-6-isopropyl-2-oxoazepan-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Antagonist activity at human CL receptor expressed in E10 cells assessed as CGRP-stimulated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W02PubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50224428(CHEMBL240904 | N-[(3R)-6-isopropyl-2-oxoazepan-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 620nMAssay Description:Antagonist activity at human CL receptor expressed in E10 cells assessed as CGRP-stimulated cAMP production in presence of 50% human serumMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9W02PubMed