null

SMILES COc1ccc(Cl)cc1NC(=O)Nc1cc(C)nc2ccccc12

InChI Key InChIKey=YBLWOZUPHDKFOT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50230005   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50230005(1-(5-chloro-2-methoxyphenyl)-3-(2-methylquinolin-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of IGF1R autophosphorylationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82RHPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50230005(1-(5-chloro-2-methoxyphenyl)-3-(2-methylquinolin-4...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of IGF1R-dependent tumor cell growth in human MCF7 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82RHPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50230005(1-(5-chloro-2-methoxyphenyl)-3-(2-methylquinolin-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of IGF1R autophosphorylation in human MCF7 cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82RHPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50230005(1-(5-chloro-2-methoxyphenyl)-3-(2-methylquinolin-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of IGF1R in growth factor-stimulated NHDFMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84CTDPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50230005(1-(5-chloro-2-methoxyphenyl)-3-(2-methylquinolin-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of recombinant IGF1R by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27944WQPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50230005(1-(5-chloro-2-methoxyphenyl)-3-(2-methylquinolin-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of IGF1R-dependent tumor cell growth in human MCNeuA cellsChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DB82RHPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50230005(1-(5-chloro-2-methoxyphenyl)-3-(2-methylquinolin-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of IGF1R autophosphorylation in human MCF7 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P84CTDPubMed