null
SMILES Cc1ccc(C(=O)c2sc3cc(O)ccc3c2Oc2ccc(\C=C\C(O)=O)cc2)c(C)c1
InChI Key InChIKey=GTHFOYIZMMEGBT-WUXMJOGZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50233215
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois College of Pharmacy
Curated by ChEMBL
University of Illinois College of Pharmacy
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]estradiol from full length recombinant human ESR1 expressed in insect cells by radiometric assayMore data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois College of Pharmacy
Curated by ChEMBL
University of Illinois College of Pharmacy
Curated by ChEMBL
Affinity DataIC50: 4.5nMAssay Description:Antagonist activity at ERalpha in tamoxifen-sensitive human MCF7:WS8 cells assessed as inhibition of estradiol-induced response after 18 hrs by lucif...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
University of Illinois College of Pharmacy
Curated by ChEMBL
University of Illinois College of Pharmacy
Curated by ChEMBL
Affinity DataEC50: 0.920nMAssay Description:Induction of ERalpha degradation in tamoxifen-sensitive human MCF7:WS8 cells after 24 hrs by CellTag 700 staining based In-cell western assayMore data for this Ligand-Target Pair