null

SMILES Clc1cccc(N2CCN(CCCC(=O)Nc3ccn4ncc(C#N)c4c3)CC2)c1Cl

InChI Key InChIKey=MBMINXDPXIMQPF-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50237164   

TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50237164(CHEMBL4091064)copy SMILEScopy InChI
Affinity DataKi:  0.520nMAssay Description:Displacement of [3H]spiperone from human Dopamine D2S receptor expressed in CHO cell membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8GR7PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50237164(CHEMBL4091064)copy SMILEScopy InChI
Affinity DataKi:  0.910nMAssay Description:Displacement of [3H]spiperone from human Dopamine D2L receptor expressed in CHO cell membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8GR7PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50237164(CHEMBL4091064)copy SMILEScopy InChI
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]spiperone from human Dopamine D3 receptor expressed in CHO cell membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8GR7PubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50237164(CHEMBL4091064)copy SMILEScopy InChI
Affinity DataKi:  5.60nMAssay Description:Inhibition of FPP incorporation into biotinylated K-Ras-derived peptide by human farnesyl transferaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8GR7PubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50237164(CHEMBL4091064)copy SMILEScopy InChI
Affinity DataKi:  32nMAssay Description:Displacement of [3H]spiperone from human Dopamine D4 receptor expressed in CHO cell membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8GR7PubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50237164(CHEMBL4091064)copy SMILEScopy InChI
Affinity DataKi:  250nMAssay Description:Displacement of [3H]SCH23390 from human Dopamine D1 receptor expressed in HEK293T cell membranes after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8GR7PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50237164(CHEMBL4091064)copy SMILEScopy InChI
Affinity DataEC50:  870nMAssay Description:Inhibitory concentration of compound against LPS- induced TNF-alpha production in whole human blood assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8GR7PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University Erlangen-N£rnberg

Curated by ChEMBL
LigandPNGBDBM50237164(CHEMBL4091064)copy SMILEScopy InChI
Affinity DataEC50:  62nMAssay Description:In vitro binding affinity against Tachykinin receptor 1 in guinea pig ileum using organ bath assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CJ8GR7PubMed