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SMILES Cc1cccc2nc(Cn3cnc4c(N)ncnc34)n(-c3ccccc3)c(=O)c12

InChI Key InChIKey=KADZMZDAUYWFBW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50239402   

LigandPNGBDBM50239402(CHEMBL4090825)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:Inhibition of 0.1 nM of [125I]- (S)-N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2-methoxy-benzamide binding in striatal homogenates of rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40XBDPubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Universit£ degli Studi di Parma

Curated by ChEMBL
LigandPNGBDBM50239402(CHEMBL4090825)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of PI3Kdelta in human PBMC assessed as reduction in anti-human CD28 antibody stimulated IL-6 secretion levels after 72 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V40XBDPubMed