null
SMILES COc1cc(OC)c(F)c(COc2cnc(Nc3c(C)cccc3NC(=O)C=C)nc2)c1F
InChI Key InChIKey=FSAPXEJFAWOTKO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50240575
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
WuXi AppTec (Shanghai) Co., Ltd.
Curated by ChEMBL
WuXi AppTec (Shanghai) Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged FGFR4 cytoplasmic domain (781 to 133 residues) expressed in baculovirus expression system using...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
WuXi AppTec (Shanghai) Co., Ltd.
Curated by ChEMBL
WuXi AppTec (Shanghai) Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human VEGFR2 using poly[Glu:Tyr] (4:1) as substrate measured after 120 mins in presence of [gamma33P]ATP by P81 ion exchange chromatogr...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
WuXi AppTec (Shanghai) Co., Ltd.
Curated by ChEMBL
WuXi AppTec (Shanghai) Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human BTK using KVEKIGEGTYGVVYK as substrate measured after 120 mins in presence of [gamma33P]ATP by P81 ion exchange chromatographic m...More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
WuXi AppTec (Shanghai) Co., Ltd.
Curated by ChEMBL
WuXi AppTec (Shanghai) Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human FMS using poly[Glu:Tyr] (4:1) as substrate measured after 120 mins in presence of [gamma33P]ATP by P81 ion exchange chromatograph...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
WuXi AppTec (Shanghai) Co., Ltd.
Curated by ChEMBL
WuXi AppTec (Shanghai) Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human JAK3 using GEEEEYFELVKKKK as substrate measured after 120 mins in presence of [gamma33P]ATP by P81 ion exchange chromatographic m...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
WuXi AppTec (Shanghai) Co., Ltd.
Curated by ChEMBL
WuXi AppTec (Shanghai) Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human TEC using poly[Glu:Tyr] (4:1) as substrate measured after 120 mins in presence of [gamma33P]ATP by P81 ion exchange chromatograph...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate pretreated for 10 mins followed by substrate addition measured after 10 ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMAssay Description:Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortexMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
WuXi AppTec (Shanghai) Co., Ltd.
Curated by ChEMBL
WuXi AppTec (Shanghai) Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 8.60E+3nMAssay Description:Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortexMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
WuXi AppTec (Shanghai) Co., Ltd.
Curated by ChEMBL
WuXi AppTec (Shanghai) Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortexMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
WuXi AppTec (Shanghai) Co., Ltd.
Curated by ChEMBL
WuXi AppTec (Shanghai) Co., Ltd.
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate pretreated for 10 mins followed by substrate addition measured after 10 m...More data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+4nMAssay Description:Concentration that inhibits the binding of radioligand, [3H]-ICS 205930, to 5-hydroxytryptamine 3 receptor from rat cortexMore data for this Ligand-Target Pair