null

SMILES CC(C)C[C@@H]1COCc2nc(OCc3cccc(c3)C#N)cc(=O)n12

InChI Key InChIKey=FIUWNNXHWOQZGO-MRXNPFEDSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50240900   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50240900(CHEMBL4091620)copy SMILEScopy InChI
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]MPEPy from human mGlu5 expressed in HEK293FT cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5HS8PubMed
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50240900(CHEMBL4091620)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Negative allosteric modulation of rat mGlu5 expressed in HEK293 cells assessed as inhibition of glutamate-induced intracellular calcium accumulation ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5HS8PubMed