null

SMILES Cc1nc2ccccc2c(=O)[nH]1

InChI Key InChIKey=FIEYHAAMDAPVCH-UHFFFAOYSA-N

PDB links: 3 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50241202   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50241202(2-Methyl-3H-quinazolin-4-one | CHEMBL395092)copy SMILEScopy InChI
Affinity DataKi:  9.90E+5nMAssay Description:Inhibition of human N-terminal His6-tagged PDE10A2 catalytic domain expressed in Escherichia coli BL21(DE3) RIL cells using 3',5'-cGMP as substrate b...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Vrije Universiteit Amsterdam

Curated by ChEMBL
LigandPNGBDBM50241202(2-Methyl-3H-quinazolin-4-one | CHEMBL395092)copy SMILEScopy InChI
Affinity DataKi:  9.90E+5nMAssay Description:Inhibition of human N-terminal His6-tagged PDE10A2 catalytic domain expressed in Escherichia coli BL21(DE3) RIL cells using 3',5'-cGMP as substrate b...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Università di Perugia

Curated by ChEMBL
LigandPNGBDBM50241202(2-Methyl-3H-quinazolin-4-one | CHEMBL395092)copy SMILEScopy InChI
Affinity DataIC50: 5.60E+3nMAssay Description:The compound was tested for poly(ADP-ribose)polymerase (PARP) inhibitionMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Università di Perugia

Curated by ChEMBL
LigandPNGBDBM50241202(2-Methyl-3H-quinazolin-4-one | CHEMBL395092)copy SMILEScopy InChI
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of PARP1 using TACS-Sapphire substrate for 30 mins by colorimetryMore data for this Ligand-Target Pair