null

SMILES C[C@@H]1CC[C@]2(C)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2[C@H]1C

InChI Key InChIKey=FSLPMRQHCOLESF-SFMCKYFRSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50241956   

LigandPNGBDBM50241956((3S,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bR)-4,4,6a...)copy SMILEScopy InChI
Affinity DataKi:  4.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9W3B
LigandPNGBDBM50241956((3S,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bR)-4,4,6a...)copy SMILEScopy InChI
Affinity DataKi:  6.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XG9W3B
TargetDNA topoisomerase 1(Homo sapiens (Human))
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50241956((3S,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bR)-4,4,6a...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 1-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67HW5PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Osaka University

Curated by ChEMBL
LigandPNGBDBM50241956((3S,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bR)-4,4,6a...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in insect cells assessed as decrease in production of 5-HPETE and 5-HETE using arachidonic acid as su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F1936BPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Osaka University

Curated by ChEMBL
LigandPNGBDBM50241956((3S,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bR)-4,4,6a...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in insect cells assessed as decrease in production of 5-HPETE and 5-HETE using arachidonic acid as su...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F1936BPubMed
TargetDNA topoisomerase 2-alpha(Homo sapiens (Human))
Stephen F. Austin State University

Curated by ChEMBL
LigandPNGBDBM50241956((3S,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bR)-4,4,6a...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human DNA topoisomerase 2-mediated relaxation of supercoiled DNA by gel electrophoresisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67HW5PubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Universite Louis Pasteur

Curated by ChEMBL
LigandPNGBDBM50241956((3S,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bR)-4,4,6a...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at TGR5 expressed in CHO cells by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4KDWPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50241956((3S,4aR,6aR,6bS,8aR,11R,12S,12aR,14aR,14bR)-4,4,6a...)copy SMILEScopy InChI
Affinity DataIC50: 1.93E+4nMAssay Description:Compound is evaluated for the inhibition of porcine plasma Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P271N3PubMed