null

SMILES Cc1ccc(cc1C(=O)Nc1ccc(N)nc1)C(=O)NCCC1CCCC1

InChI Key InChIKey=CLEGTVIMOPPIBR-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50243182   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50243182(CHEMBL487431 | N'-(6-aminopyridin-3-yl)-N-(2-cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 77nMAssay Description:Inhibition of c-Kit (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN44TTPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50243182(CHEMBL487431 | N'-(6-aminopyridin-3-yl)-N-(2-cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of KDR (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50243182(CHEMBL487431 | N'-(6-aminopyridin-3-yl)-N-(2-cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of Lck (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN44TTPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50243182(CHEMBL487431 | N'-(6-aminopyridin-3-yl)-N-(2-cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 77nMAssay Description:Inhibition of c-kit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20001WPPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50243182(CHEMBL487431 | N'-(6-aminopyridin-3-yl)-N-(2-cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen Inc.

Curated by ChEMBL
LigandPNGBDBM50243182(CHEMBL487431 | N'-(6-aminopyridin-3-yl)-N-(2-cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 998nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20001WPPubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Amgen Inc

Curated by ChEMBL
LigandPNGBDBM50243182(CHEMBL487431 | N'-(6-aminopyridin-3-yl)-N-(2-cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Src (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DN44TTPubMed