null
SMILES COCCS(=O)(=O)N[C@H]1C[C@H](C1)N(C)c1ncnc2[nH]ccc12
InChI Key InChIKey=KQVAWOMGNFKYNP-PHIMTYICSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50243838
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2/Tyrosine-protein kinase JAK1(Homo sapiens (Human))
Pfizer Inc.
Curated by ChEMBL
Pfizer Inc.
Curated by ChEMBL
Affinity DataIC50: 628nMAssay Description:The ability to inhibit [3H]-SCH- 23390 binding to Dopamine receptor D1 in rat striataMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of recombinant human JAK2 using FITC-KGGEEEEYFELVKK as substrate in presence of 1 mM ATP by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:Inhibition of recombinant human JAK1 using 5'FAM-KKSRGDYMTMQID as substrate in presence of 1 mM ATP by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.56E+4nMAssay Description:Compound was evaluated for the binding affinity to Endothelin B receptor in the rat cerebellumMore data for this Ligand-Target Pair