null

SMILES CC(C)(C)c1ccc(cc1)-c1nc2c(cccc2[nH]1)N1CCN(Cc2cccc3[nH]c(=S)[nH]c23)CC1

InChI Key InChIKey=LMDJCZQDFNSVLY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50244135   

TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244135(4-{4-[2-(4-tert-Butyl-phenyl)-1H-benzoimidazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from rat recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244135(4-{4-[2-(4-tert-Butyl-phenyl)-1H-benzoimidazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Antagonist activity at recombinant GnRH receptor in CO2 asphyxiated rat primary pituitary cells assessed as reduction in (D-Trp6)LHRH-induced LH rele...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244135(4-{4-[2-(4-tert-Butyl-phenyl)-1H-benzoimidazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Antagonist activity at human recombinant GnRH receptor assessed as reduction in (D-Trp6)LHRH-induced myo-(1,2)-[3H]inositol productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50244135(4-{4-[2-(4-tert-Butyl-phenyl)-1H-benzoimidazol-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Displacement of [125I]-(D-Trp6)LHRH from human recombinant GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB52Q7PubMed