null
SMILES OC(=O)CCn1c2ccc(O)cc2c2c3C(=O)NC(=O)c3c(cc12)-c1ccccc1
InChI Key InChIKey=JDARUOOLJCFUOY-UHFFFAOYSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50245344
TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of Chk1 kinase assessed as GST-Cdc25 phosphorylation by Western blot determinationMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of human Wee1 assessed as polyornithine-tyrosine copolymer phosphorylationMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q26M36MCPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q26M36MCPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of Auckland
Curated by ChEMBL
University of Auckland
Curated by ChEMBL
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of c-SrcMore data for this Ligand-Target Pair