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SMILES Oc1ccc2n(CCc3nnn[nH]3)c3cc(c4C(=O)NC(=O)c4c3c2c1)-c1ccccc1Cl

InChI Key InChIKey=FGWIZMZCHKMCBT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50245423   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50245423(4-(2-Chlorophenyl)-9-hydroxy-6-[2-(1H-tetrazol-5-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Chk1 kinase assessed as GST-Cdc25 phosphorylation by Western blot determinationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M36MCPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50245423(4-(2-Chlorophenyl)-9-hydroxy-6-[2-(1H-tetrazol-5-y...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Cdc2 Tyr15 phosphorylation in human HT29 cells by western blotMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M36MCPubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50245423(4-(2-Chlorophenyl)-9-hydroxy-6-[2-(1H-tetrazol-5-y...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of human Wee1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34XB6PubMed
TargetWee1-like protein kinase(Homo sapiens (Human))
Chulalongkorn University

Curated by ChEMBL
LigandPNGBDBM50245423(4-(2-Chlorophenyl)-9-hydroxy-6-[2-(1H-tetrazol-5-y...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of human Wee1 assessed as polyornithine-tyrosine copolymer phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M36MCPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50245423(4-(2-Chlorophenyl)-9-hydroxy-6-[2-(1H-tetrazol-5-y...)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of Cdc2 Tyr15 phosphorylation in human HT29 cells by Western blotMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M36MCPubMed