null
SMILES COC(=O)Cn1c2c(C)cc(C)cc2n(CC(=O)Nc2ccc3C[C@]4(Cc3c2)N(C)C(=O)NC4=O)c1=O
InChI Key InChIKey=DVWHBSJZSHVOSH-AREMUKBSSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50246271
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataKi: 2.10nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK93 cellsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 5.60nMAssay Description:Antagonist activity against human cloned CGRP receptor expressed in HEK93 cells assessed as inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Antagonist activity against human cloned CGRP receptor expressed in HEK93 cells assessed as inhibition of CGRP-induced cAMP production in presence of...More data for this Ligand-Target Pair