null
SMILES CN1C(=O)NC(=O)[C@]11Cc2ccc(NC(=O)Cn3c4cccc5NC(=O)Cn(c45)c3=O)cc2C1
InChI Key InChIKey=ZAMUDFHSMUEORA-HSZRJFAPSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50246422
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataKi: 0.510nMAssay Description:Displacement of [125I]hCGRP from human cloned CGRP receptor expressed in HEK93 cellsMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataKi: 0.510nMAssay Description:Displacement of [125I]human CLR from human CGRP expressed in HEK293 cells coexpressing human RAMP1More data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Antagonist activity at human CLR expressed in human HEK293 cells coexpressing human RAMP1 assessed as Inhibition of CGRP-induced cAMP production in t...More data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Antagonist activity at human CLR expressed in human HEK293 cells coexpressing human RAMP1 assessed as Inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 5.40nMAssay Description:Antagonist activity against human cloned CGRP receptor expressed in HEK93 cells assessed as inhibition of CGRP-induced cAMP production in presence of...More data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck & Co.
Curated by ChEMBL
Merck & Co.
Curated by ChEMBL
Affinity DataIC50: 2.40nMAssay Description:Antagonist activity against human cloned CGRP receptor expressed in HEK93 cells assessed as inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair