null

SMILES NC(=N)SCCCn1c(=O)c2c(n3c(cc4ccccc34)c3cccc4ccn2c34)c1=O

InChI Key InChIKey=RUTCIZOQGCWURK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50246774   

TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human VEGFR3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7VH4PubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human AXLMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7VH4PubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human AKT1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7VH4PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human CDK2/Cyc2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7VH4PubMed
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human CDK4/CycD1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7VH4PubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human METMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7VH4PubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7VH4PubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of human PLK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7VH4PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human SRCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7VH4PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7VH4PubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human EPHB4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7VH4PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of human ERBB2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7VH4PubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human FAKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7VH4PubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7VH4PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7VH4PubMed
TargetInsulin receptor(Homo sapiens (Human))
Institute of General Genetics

Curated by ChEMBL
LigandPNGBDBM50246774(3-(1,3-Dioxo-1,3-dihydro-2H-indolo[1',7':4,5,6]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human INSRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7VH4PubMed