null

SMILES NC(C(OCc1ccccc1)C(O)=O)C(O)=O

InChI Key InChIKey=BYOBCYXURWDEDS-UHFFFAOYSA-N

PDB links: 5 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50247191   

TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Institute for Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50247191((2S,3S)-2-Amino-3-benzyloxy-succinic acid | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 3Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CR5TVNPubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Institute for Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50247191((2S,3S)-2-Amino-3-benzyloxy-succinic acid | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 5.13E+3nMAssay Description:Inhibition of human EAAT3 transfected in HEK293 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 4 mins by TopCount scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2TQZPubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Institute for Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50247191((2S,3S)-2-Amino-3-benzyloxy-succinic acid | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+4nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 1Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CR5TVNPubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Institute for Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50247191((2S,3S)-2-Amino-3-benzyloxy-succinic acid | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of glutamate-induced depolarization in human EAAT1 expressed in HEK293 cells by FMP assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95FCPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Universite Blaise Pascal

Curated by ChEMBL
LigandPNGBDBM50247191((2S,3S)-2-Amino-3-benzyloxy-succinic acid | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of glutamate-induced depolarization in human human EAAT2 expressed in HEK293 cells by FMP assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95FCPubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Institute for Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50247191((2S,3S)-2-Amino-3-benzyloxy-succinic acid | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of glutamate-induced depolarization in human human EAAT3 expressed in HEK293 cells by FMP assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M95FCPubMed
TargetGlutamate transporter homolog(Pyrococcus horikoshii (strain ATCC 700860 / DSM 12...)
Columbia University

Curated by ChEMBL
LigandPNGBDBM50247191((2S,3S)-2-Amino-3-benzyloxy-succinic acid | CHEMBL...)copy SMILEScopy InChI
Affinity DataKd:  100nMAssay Description:Binding affinity to Pyrococcus horikoshii sodium-coupled aspartate transporter D405N mutant in presence of NaClMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 4(Rattus norvegicus)TBA
LigandPNGBDBM50247191((2S,3S)-2-Amino-3-benzyloxy-succinic acid | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of rat EAAT4 transfected in human tsA201 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 4 mins by TopCount scintill...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2TQZPubMed
TargetExcitatory amino acid transporter 4(Rattus norvegicus)TBA
LigandPNGBDBM50247191((2S,3S)-2-Amino-3-benzyloxy-succinic acid | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 3.89E+3nMAssay Description:Inhibition of rat EAAT4 transfected in human tsA201 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 4 mins by TopCount scintill...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2TQZPubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Institute for Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50247191((2S,3S)-2-Amino-3-benzyloxy-succinic acid | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human EAAT1 transfected in HEK293 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 4 mins by TopCount scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2TQZPubMed
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Institute for Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50247191((2S,3S)-2-Amino-3-benzyloxy-succinic acid | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of human EAAT1 transfected in HEK293 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 4 mins by TopCount scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2TQZPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Universite Blaise Pascal

Curated by ChEMBL
LigandPNGBDBM50247191((2S,3S)-2-Amino-3-benzyloxy-succinic acid | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human EAAT2 transfected in HEK293 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 4 mins by TopCount scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2TQZPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Universite Blaise Pascal

Curated by ChEMBL
LigandPNGBDBM50247191((2S,3S)-2-Amino-3-benzyloxy-succinic acid | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of human EAAT2 transfected in HEK293 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 4 mins by TopCount scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2TQZPubMed
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Institute for Bioorganic Research

Curated by ChEMBL
LigandPNGBDBM50247191((2S,3S)-2-Amino-3-benzyloxy-succinic acid | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human EAAT3 transfected in HEK293 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 4 mins by TopCount scintillatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2TQZPubMed
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Universite Blaise Pascal

Curated by ChEMBL
LigandPNGBDBM50247191((2S,3S)-2-Amino-3-benzyloxy-succinic acid | CHEMBL...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 2Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CR5TVNPubMed