null
SMILES NC(C(OCc1ccccc1)C(O)=O)C(O)=O
InChI Key InChIKey=BYOBCYXURWDEDS-UHFFFAOYSA-N
PDB links: 5 PDB IDs match this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50247191
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Institute for Bioorganic Research
Curated by ChEMBL
Institute for Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 3Checked by AuthorMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Institute for Bioorganic Research
Curated by ChEMBL
Institute for Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 5.13E+3nMAssay Description:Inhibition of human EAAT3 transfected in HEK293 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 4 mins by TopCount scintillatio...More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Institute for Bioorganic Research
Curated by ChEMBL
Institute for Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 4.80E+4nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 1Checked by AuthorMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Institute for Bioorganic Research
Curated by ChEMBL
Institute for Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of glutamate-induced depolarization in human EAAT1 expressed in HEK293 cells by FMP assayChecked by AuthorMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Universite Blaise Pascal
Curated by ChEMBL
Universite Blaise Pascal
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of glutamate-induced depolarization in human human EAAT2 expressed in HEK293 cells by FMP assayChecked by AuthorMore data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Institute for Bioorganic Research
Curated by ChEMBL
Institute for Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of glutamate-induced depolarization in human human EAAT3 expressed in HEK293 cells by FMP assayChecked by AuthorMore data for this Ligand-Target Pair
TargetGlutamate transporter homolog(Pyrococcus horikoshii (strain ATCC 700860 / DSM 12...)
Columbia University
Curated by ChEMBL
Columbia University
Curated by ChEMBL
Affinity DataKd: 100nMAssay Description:Binding affinity to Pyrococcus horikoshii sodium-coupled aspartate transporter D405N mutant in presence of NaClMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of rat EAAT4 transfected in human tsA201 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 4 mins by TopCount scintill...More data for this Ligand-Target Pair
Affinity DataIC50: 3.89E+3nMAssay Description:Inhibition of rat EAAT4 transfected in human tsA201 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 4 mins by TopCount scintill...More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Institute for Bioorganic Research
Curated by ChEMBL
Institute for Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human EAAT1 transfected in HEK293 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 4 mins by TopCount scintillatio...More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 1(Homo sapiens (Human))
Institute for Bioorganic Research
Curated by ChEMBL
Institute for Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of human EAAT1 transfected in HEK293 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 4 mins by TopCount scintillatio...More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Universite Blaise Pascal
Curated by ChEMBL
Universite Blaise Pascal
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human EAAT2 transfected in HEK293 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 4 mins by TopCount scintillatio...More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Universite Blaise Pascal
Curated by ChEMBL
Universite Blaise Pascal
Curated by ChEMBL
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of human EAAT2 transfected in HEK293 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 4 mins by TopCount scintillatio...More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 3(Homo sapiens (Human))
Institute for Bioorganic Research
Curated by ChEMBL
Institute for Bioorganic Research
Curated by ChEMBL
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human EAAT3 transfected in HEK293 cells assessed as inhibition of [3H]-D-aspartate uptake incubated for 4 mins by TopCount scintillatio...More data for this Ligand-Target Pair
TargetExcitatory amino acid transporter 2(Homo sapiens (Human))
Universite Blaise Pascal
Curated by ChEMBL
Universite Blaise Pascal
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Concentration required for blocking [14C]glutamate uptake in COS-1 cells expressing human Excitatory amino acid transporter 2Checked by AuthorMore data for this Ligand-Target Pair