null

SMILES O=C(NCC(=O)N1CCCC1)Nc1ccc2cnccc2c1

InChI Key InChIKey=DMIDPTCQPIJYFE-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50247349   

TargetProtein arginine N-methyltransferase 3(Homo sapiens)
Icahn School of Medicine at Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50247349(CHEMBL4072005)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of PRMT3 (unknown origin) using C-terminally biotinylated histone H4 as substrate in presence of [3H]S-adenosylmethionine by scintillation...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
Icahn School of Medicine at Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50247349(CHEMBL4072005)copy SMILEScopy InChI
Affinity DataIC50: 91nMAssay Description:Inhibition of FLAG-tagged wild type human PRMT3 expressed in HEK293 cells assessed as decrease in exogenous H4R3 dimethylation level using GFP-tagged...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
Icahn School of Medicine at Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50247349(CHEMBL4072005)copy SMILEScopy InChI
Affinity DataIC50: 225nMAssay Description:Inhibition of FLAG-tagged wild type human PRMT3 expressed in HEK293 cells assessed as reduction in endogenous H4R3me2a level using GFP-tagged histone...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
Icahn School of Medicine at Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50247349(CHEMBL4072005)copy SMILEScopy InChI
Affinity DataEC50:  2.00E+3nMAssay Description:Binding affinity to beta galactosidase fused human PRMT3 (211 to 531 residues) expressed in human A549 cells after 6 hrs by InCELL hunter assayMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
Icahn School of Medicine at Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50247349(CHEMBL4072005)copy SMILEScopy InChI
Affinity DataEC50:  1.80E+3nMAssay Description:Binding affinity to beta galactosidase fused human PRMT3 (211 to 531 residues) expressed in human HEK293 cells after 6 hrs by InCELL hunter assayMore data for this Ligand-Target Pair