null
SMILES FC1(F)CN(CC1(F)F)C(=O)CNC(=O)Nc1ccc2cnccc2c1
InChI Key InChIKey=UFDKSBSTTLCMOV-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50247359
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of FLAG-tagged wild type human PRMT3 expressed in HEK293 cells assessed as decrease in exogenous H4R3 dimethylation level using GFP-tagged...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of PRMT3 (unknown origin) using C-terminally biotinylated histone H4 as substrate in presence of [3H]S-adenosylmethionine by scintillation...More data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
Affinity DataEC50: 2.70E+3nMAssay Description:Binding affinity to beta galactosidase fused human PRMT3 (211 to 531 residues) expressed in human A549 cells after 6 hrs by InCELL hunter assayMore data for this Ligand-Target Pair
TargetProtein arginine N-methyltransferase 3(Homo sapiens)
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
Icahn School of Medicine at Mount Sinai
Curated by ChEMBL
Affinity DataEC50: 3.10E+3nMAssay Description:Binding affinity to beta galactosidase fused human PRMT3 (211 to 531 residues) expressed in human HEK293 cells after 6 hrs by InCELL hunter assayMore data for this Ligand-Target Pair