null

SMILES Fc1ccccc1Sc1ccc(C#N)c(c1)C(F)(F)F

InChI Key InChIKey=OZEYWYWKQCOUOK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50248594   

TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50248594(4-(2-Fluorophenylthio)-2-(trifluoromethyl)benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 184nMAssay Description:Displacement of [3H]DHT from human cloned androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GDVPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50248594(4-(2-Fluorophenylthio)-2-(trifluoromethyl)benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Antagonist activity at human androgen receptor expressed in human MDA-MB453 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0GDVPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50248594(4-(2-Fluorophenylthio)-2-(trifluoromethyl)benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 184nMAssay Description:Displacement of [3H]DHT from human AR expressed in baculovirus Sf9 cells system by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50248594(4-(2-Fluorophenylthio)-2-(trifluoromethyl)benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Antagonist activity at androgen receptor in human MDA-MB-453 cells coexpressing MMTV-ARE reporter gene assessed as inhibition of DHT-induced responseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50248594(4-(2-Fluorophenylthio)-2-(trifluoromethyl)benzonit...)copy SMILEScopy InChI
Affinity DataIC50: 6.95E+3nMAssay Description:Binding affinity to progesterone receptor by PRB assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1K1TPubMed