null
SMILES Fc1ccccc1Sc1ccc(C#N)c(c1)C(F)(F)F
InChI Key InChIKey=OZEYWYWKQCOUOK-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50248594
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 184nMAssay Description:Displacement of [3H]DHT from human cloned androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Antagonist activity at human androgen receptor expressed in human MDA-MB453 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 184nMAssay Description:Displacement of [3H]DHT from human AR expressed in baculovirus Sf9 cells system by scintillation countingMore data for this Ligand-Target Pair
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development
Curated by ChEMBL
Pfizer Global Research and Development
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Antagonist activity at androgen receptor in human MDA-MB-453 cells coexpressing MMTV-ARE reporter gene assessed as inhibition of DHT-induced responseMore data for this Ligand-Target Pair
TargetProgesterone receptor(Homo sapiens (Human))
Pfizer Global Research& Development
Curated by ChEMBL
Pfizer Global Research& Development
Curated by ChEMBL
Affinity DataIC50: 6.95E+3nMAssay Description:Binding affinity to progesterone receptor by PRB assayMore data for this Ligand-Target Pair