null

SMILES Fc1ccc(Nc2ccc3c(CCc4ccccc4C3=O)c2)c(F)c1

InChI Key InChIKey=ONKRGPPYJKVSHA-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50248859   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-Universität

Curated by ChEMBL
LigandPNGBDBM50248859(2-(2,4-Difluoro-phenylamino)-10,11-dihydro-dibenzo...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) by cell-free enzyme immunosorbent assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21836C7PubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-Universität

Curated by ChEMBL
LigandPNGBDBM50248859(2-(2,4-Difluoro-phenylamino)-10,11-dihydro-dibenzo...)copy SMILEScopy InChI
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of p38alpha MAP kinase in human whole blood assessed as inhibition of LPS-induced TNFalpha release by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81H2CPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-Universität

Curated by ChEMBL
LigandPNGBDBM50248859(2-(2,4-Difluoro-phenylamino)-10,11-dihydro-dibenzo...)copy SMILEScopy InChI
Affinity DataIC50: 95nMAssay Description:Competitive inhibition of p38alpha MAP kinase (unknown origin) in presence of 100 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q81H2CPubMed