null

SMILES CC(C)(C)n1nc(Cc2cc(F)cc(F)c2)c2c(N)ncnc12

InChI Key InChIKey=GFAVGLXIXAHTSJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50249994   

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of California

Curated by ChEMBL
LigandPNGBDBM50249994(CHEMBL2324593 | US11208411, Compound CZ75)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of C-terminal His-tagged full length Toxoplasma gondii CDPK1 expressed in Escherichia coli BL21 (DE3) using syntide-2 as substrate pre-inc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PP0PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))TBA
LigandPNGBDBM50249994(CHEMBL2324593 | US11208411, Compound CZ75)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Full length CDPK1 was PCR amplified from a T. gondii RH cDNA library generated using the SMART cDNA synthesis kit (Clontech). The primers contained r...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21G0QGQUS Patent
TargetCAM kinase, CDPK family TgCDPK1(Toxoplasma gondii (strain ATCC 50861 / VEG))TBA
LigandPNGBDBM50249994(CHEMBL2324593 | US11208411, Compound CZ75)copy SMILEScopy InChI
Affinity DataIC50: 31.9nMAssay Description:Full length CDPK1 was PCR amplified from a T. gondii RH cDNA library generated using the SMART cDNA synthesis kit (Clontech). The primers contained r...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21G0QGQUS Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))TBA
LigandPNGBDBM50249994(CHEMBL2324593 | US11208411, Compound CZ75)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Src kinase domain (254 to 536 residues) expressed in Escherichia coli BL21 (DE3) using abltide as substrate pre-incubated for 10 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PP0PubMed