null
SMILES COCCn1cc(-c2ccncc2)c2ccncc12
InChI Key InChIKey=OVRGOPVESVCREL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50251436
TargetNuclear factor of activated T-cells, cytoplasmic 1(Homo sapiens)
Rigel Pharmaceuticals, Inc.
Curated by ChEMBL
Rigel Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataEC50: 6.90E+3nMAssay Description:Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Rigel Pharmaceuticals, Inc.
Curated by ChEMBL
Rigel Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of full-length recombinant human His-tagged GSK3B recombinant in baculovirus expression system using Alexa-Fluor tracer-236 incubated for ...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation (GNF)
Curated by ChEMBL
Genomics Institute of the Novartis Research Foundation (GNF)
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG expressed in CHO cells incubated for 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation (GNF)
Curated by ChEMBL
Genomics Institute of the Novartis Research Foundation (GNF)
Curated by ChEMBL
Affinity DataIC50: 272nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK1A (1 to 763 residues) expressed in Sf21 cells using Ulight-glycogen synthase as substrate ...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Rigel Pharmaceuticals, Inc.
Curated by ChEMBL
Rigel Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataIC50: 2.96E+4nMAssay Description:Inhibition of recombinant human His/GST-tagged GSK3beta (2 to 433 residues) expressed in baculovirus infected Sf9 cells using Ulight-glycogen synthas...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Genomics Institute of the Novartis Research Foundation (GNF)
Curated by ChEMBL
Genomics Institute of the Novartis Research Foundation (GNF)
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of full-length recombinant human GST-tagged Dyrk1a expressed in baculovirus expression system using Alexa-Fluor tracer-236 incubated for 6...More data for this Ligand-Target Pair