null
SMILES OCCN(Cc1ccc(cc1)C(=O)NO)C(=O)Cc1ccccc1
InChI Key InChIKey=GTFAUKGKYICUDS-UHFFFAOYSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50252388
TargetHistone deacetylase 6(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of human HDAC6 after 15 mins by trypsin-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of human HDAC1 after 15 mins by trypsin-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human HDAC2 after 15 mins by trypsin-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 3(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human HDAC3 after 15 mins by by trypsin-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 4(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human HDAC4 after 15 mins by trypsin-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 7(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human HDAC7 after 15 mins by trypsin-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 376nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
TargetPolyamine deacetylase HDAC10(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of human HDAC10 after 15 mins by trypsin-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 11(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human HDAC11 after 15 mins by trypsin-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 5(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of human HDAC5 after 15 mins by trypsin-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of human HDAC8 after 15 mins by trypsin-coupled fluorescence assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 insect cells assessed as decrease in re...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of recombinant human full length C-terminal His/FLAG-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells assessed as decrease ...More data for this Ligand-Target Pair
TargetHistone deacetylase 9(Homo sapiens (Human))
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
SynBioC Research Group, Department of Sustainable Organic Chemistry and Technology, Faculty of Bioscience Engineering, Ghent University, Coupure Links 653, B-9000 Ghent, Belgium.
Curated by ChEMBL
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human HDAC9 after 15 mins by trypsin-coupled fluorescence assayMore data for this Ligand-Target Pair