null

SMILES CC(C)CN1CC(=Cc2cc(ccc2C1=O)-c1ccc(C)cc1)C(=O)Nc1ccc(CN(C)C2CCOCC2)cc1

InChI Key InChIKey=QWKBLVGDYWYJNQ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50252431   

TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institut für Pharmazeutische und Medizinische Chemie der Westfälischen Wilhelms-Universität Münster, Corrensstraße 48, D-48149 Münster, Germany.

Curated by ChEMBL
LigandPNGBDBM50252431(CHEMBL4070869)copy SMILEScopy InChI
Affinity DataIC50: 387nMAssay Description:Displacement of [3H]INCB3344 from human CCR2 expressed in human U2OS cells after 120 mins by scintillation spectrometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60RH6PubMed
TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Institut für Pharmazeutische und Medizinische Chemie der Westfälischen Wilhelms-Universität Münster, Corrensstraße 48, D-48149 Münster, Germany.

Curated by ChEMBL
LigandPNGBDBM50252431(CHEMBL4070869)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Antagonist activity at human CCR2b expressed in human Chem1 cells assessed as inhibition of human recombinant CCL2 induced Ca2+ mobilization preincub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60RH6PubMed
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
Institut für Pharmazeutische und Medizinische Chemie der Westfälischen Wilhelms-Universität Münster, Corrensstraße 48, D-48149 Münster, Germany.

Curated by ChEMBL
LigandPNGBDBM50252431(CHEMBL4070869)copy SMILEScopy InChI
Affinity DataEC50: >10nMAssay Description:Displacement of [125I]RANTES from human CCR5 expressed in CHO cells after 40 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60RH6PubMed