null
SMILES OC(=O)c1cccc(NC(=O)CCNC(=O)CCNCc2ccc(c(Cl)c2)-c2ccccc2)c1
InChI Key InChIKey=NZDQDPKZQDWCOF-UHFFFAOYSA-N
PDB links: 2 PDB IDs match this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50252622
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
Curated by ChEMBL
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of CK2alpha (unknown origin) using RRRADDSDDDD as substrate after 40 mins by ADP-Glo assayMore data for this Ligand-Target Pair
3D Structure (crystal)TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
Curated by ChEMBL
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
Curated by ChEMBL
Affinity DataKd: 320nMAssay Description:Binding affinity to human CK2alpha expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha/beta(Homo sapiens (Human))
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
Curated by ChEMBL
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
Curated by ChEMBL
Affinity DataKd: 310nMAssay Description:Binding affinity to CK2alpha/beta (unknown origin) expressed in Escherichia coli BL21(DE3) by ITCMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
Curated by ChEMBL
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
Curated by ChEMBL
TargetCasein kinase II subunit alpha/beta(Homo sapiens (Human))
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
Curated by ChEMBL
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
Curated by ChEMBL
Affinity DataIC50: 670nMAssay Description:Inhibition of CK2alpha/beta (unknown origin) expressed in Escherichia coli BL21(DE3) using RRRADDSDDDD as substrate after 40 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
Curated by ChEMBL
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of recombinant human CK2alpha (1 to 336 residues) expressed in Escherichia coli BL21 (DE3) using RRADDSDDDD as substrate incubated for 10 ...More data for this Ligand-Target Pair
TargetCasein kinase II subunit alpha(Homo sapiens (Human))
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
Curated by ChEMBL
Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
Curated by ChEMBL
Affinity DataKd: 320nMAssay Description:Binding affinity to CK2alpha (unknown origin) by ITCMore data for this Ligand-Target Pair