null

SMILES CC(C)Oc1nncc2cc(ccc12)-c1cc(ccc1C)C(=O)NC1CC1

InChI Key InChIKey=PRMZAUJLQXIACS-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50252781   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50252781(CHEMBL493670 | N-Cyclopropyl-4-methyl-3-(1-(1-meth...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of p38alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2PTNPubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50252781(CHEMBL493670 | N-Cyclopropyl-4-methyl-3-(1-(1-meth...)copy SMILEScopy InChI
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of KDR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2PTNPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50252781(CHEMBL493670 | N-Cyclopropyl-4-methyl-3-(1-(1-meth...)copy SMILEScopy InChI
Affinity DataIC50: 3.61E+3nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2PTNPubMed
TargetMitogen-activated protein kinase 10(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50252781(CHEMBL493670 | N-Cyclopropyl-4-methyl-3-(1-(1-meth...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2PTNPubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50252781(CHEMBL493670 | N-Cyclopropyl-4-methyl-3-(1-(1-meth...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2PTNPubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50252781(CHEMBL493670 | N-Cyclopropyl-4-methyl-3-(1-(1-meth...)copy SMILEScopy InChI
Affinity DataIC50: 5.95E+3nMAssay Description:Inhibition of JNK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2PTNPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Amgen, Inc.

Curated by ChEMBL
LigandPNGBDBM50252781(CHEMBL493670 | N-Cyclopropyl-4-methyl-3-(1-(1-meth...)copy SMILEScopy InChI
Affinity DataIC50: 421nMAssay Description:Inhibition of cKit (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2PTNPubMed