null
SMILES Cl.Cl.CN(C)Cc1nc2cc(sc2c(=O)[nH]1)-c1c[nH]nc1C
InChI Key InChIKey=KYJOLQPJQXRUOO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50253753
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company, Ltd.
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged ROCK1 catalytic domain (1 to 477 residues) expressed in baculovirus expression system using Bio...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company, Ltd.
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of Cdc7 in human HeLa cells assessed as reduction in MCM2 phosphorylation at ser40 residues after 7 hrs by Western blot analysisMore data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company, Ltd.
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company, Ltd.
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company, Ltd.
Curated by ChEMBL
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of full length human CDC2 (1 to 298 residues)/human N-terminal GST-tagged CyclinE1 (1 to 410 residues) expressed in baculovirus expression...More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company, Ltd.
Curated by ChEMBL
Affinity DataIC50: 2.20nMAssay Description:Inhibition of recombinant human full length Cdc7 (1 to 574 residues)/human N-terminal GST-tagged ASK (1 to 674 residues) expressed in baculovirus exp...More data for this Ligand-Target Pair