null

SMILES NCC[C@@H](Oc1ccc(cc1)C(F)(F)F)c1ccccc1

InChI Key InChIKey=WIQRCHMSJFFONW-OAHLLOKOSA-N

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50254791   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50254791((R)-Norfluoxetine | CHEMBL446084)copy SMILEScopy InChI
Affinity DataKi:  26nMAssay Description:Displacement of [125I]RTI55 from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50254791((R)-Norfluoxetine | CHEMBL446084)copy SMILEScopy InChI
Affinity DataKi:  3.66E+3nMAssay Description:Displacement of [125I]RTI55 from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50254791((R)-Norfluoxetine | CHEMBL446084)copy SMILEScopy InChI
Affinity DataKi:  7.49E+3nMAssay Description:Displacement of [125I]RTI55 from human recombinant NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50254791((R)-Norfluoxetine | CHEMBL446084)copy SMILEScopy InChI
Affinity DataIC50: 7.13E+3nMAssay Description:Inhibition of [3H]DA from human recombinant DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50254791((R)-Norfluoxetine | CHEMBL446084)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of [3H]5HT from human recombinant SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human BioMolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50254791((R)-Norfluoxetine | CHEMBL446084)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of [3H]NE from human recombinant NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ04Q0PubMed