null

SMILES CN1C(=O)NC(=O)[C@]11Cc2ccc(NC(=O)Cn3c4ccccc4n(C4CCSCC4)c3=O)cc2C1

InChI Key InChIKey=WMTYFICXHNNNJD-AREMUKBSSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50254979   

TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck& Co

Curated by ChEMBL
LigandPNGBDBM50254979((R)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imida...)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Displacement of [125I]hCGRP from human CGRP receptor expressed in HEK293 cells coexpressing RAMP1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1XSKPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck& Co

Curated by ChEMBL
LigandPNGBDBM50254979((R)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imida...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Antagonistic activity at human CGRP receptor expressed in HEK293 cells coexpressing RAMP1 assessed as inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1XSKPubMed
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck& Co

Curated by ChEMBL
LigandPNGBDBM50254979((R)-N-(3-methyl-2,5-dioxo-1',3'-dihydrospiro[imida...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Antagonistic activity at human CGRP receptor expressed in HEK293 cells coexpressing RAMP1 assessed as inhibition of CGRP-induced cAMP production in p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1XSKPubMed