null
SMILES O=C(Cn1c2ccccc2n(C2CCOC2)c1=O)Nc1ccc2C[C@@]3(Cc2c1)C(=O)Nc1ncccc31
InChI Key InChIKey=ZBZITUCFAIMGPC-GPIXMLASSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50255037
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck& Co
Curated by ChEMBL
Merck& Co
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [125I]hCGRP from human CGRP receptor expressed in HEK293 cells coexpressing RAMP1More data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck& Co
Curated by ChEMBL
Merck& Co
Curated by ChEMBL
Affinity DataIC50: 5.20nMAssay Description:Antagonistic activity at human CGRP receptor expressed in HEK293 cells coexpressing RAMP1 assessed as inhibition of CGRP-induced cAMP productionMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck& Co
Curated by ChEMBL
Merck& Co
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Antagonistic activity at human CGRP receptor expressed in HEK293 cells coexpressing RAMP1 assessed as inhibition of CGRP-induced cAMP production in p...More data for this Ligand-Target Pair