null

SMILES O=C(CN1CCCC2=C1C(=O)N(C1CC1)C2=O)Nc1ccc(nn1)-c1cccnc1

InChI Key InChIKey=LJDCIVDNJQNMRY-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50257128   

TargetCytochrome P450 1A2(Homo sapiens (Human))
Experimental Therapeutics Centre , 31 Biopolis Way, No. 03-01 Nanos, 138669, Singapore.

Curated by ChEMBL
LigandPNGBDBM50257128(CHEMBL4087906)copy SMILEScopy InChI
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Experimental Therapeutics Centre , 31 Biopolis Way, No. 03-01 Nanos, 138669, Singapore.

Curated by ChEMBL
LigandPNGBDBM50257128(CHEMBL4087906)copy SMILEScopy InChI
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetDual specificity mitogen-activated protein kinase kinase 5(Homo sapiens (Human))
Experimental Therapeutics Centre , 31 Biopolis Way, No. 03-01 Nanos, 138669, Singapore.

Curated by ChEMBL
LigandPNGBDBM50257128(CHEMBL4087906)copy SMILEScopy InChI
Affinity DataKd:  1.30E+3nMAssay Description:Inhibition of partial length human MEK5 expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetStefin-3(Mus musculus)TBA
LigandPNGBDBM50257128(CHEMBL4087906)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Antagonistic activity against histamine H3 receptor in guinea pig ileumMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetSerine/threonine-protein kinase RIO2(Homo sapiens (Human))
Experimental Therapeutics Centre , 31 Biopolis Way, No. 03-01 Nanos, 138669, Singapore.

Curated by ChEMBL
LigandPNGBDBM50257128(CHEMBL4087906)copy SMILEScopy InChI
Affinity DataKd:  7.40E+3nMAssay Description:Inhibition of partial length human RIOK2 expressed in mammalian expression system by KINOMEscan assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Experimental Therapeutics Centre , 31 Biopolis Way, No. 03-01 Nanos, 138669, Singapore.

Curated by ChEMBL
LigandPNGBDBM50257128(CHEMBL4087906)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Experimental Therapeutics Centre , 31 Biopolis Way, No. 03-01 Nanos, 138669, Singapore.

Curated by ChEMBL
LigandPNGBDBM50257128(CHEMBL4087906)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Homo sapiens (Human))
Experimental Therapeutics Centre , 31 Biopolis Way, No. 03-01 Nanos, 138669, Singapore.

Curated by ChEMBL
LigandPNGBDBM50257128(CHEMBL4087906)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of porcupine (unknown origin) expressed in HEK293 cells after day 1 post treatment by Super-top flash reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FF5PubMed