null

SMILES Cc1[nH]ncc1-c1cc(ccc1Oc1ccc(cc1C#N)S(=O)(=O)Nc1ncns1)C(F)(F)F

InChI Key InChIKey=WQSUNLAAABNZKE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50257167   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257167(CHEMBL2325619)copy SMILEScopy InChI
Affinity DataIC50: 737nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257167(CHEMBL2325619)copy SMILEScopy InChI
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of human NaV1.5 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50257167(CHEMBL2325619)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of NaV1.7 ion channel (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445QD6PubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.

Curated by ChEMBL
LigandPNGBDBM50257167(CHEMBL2325619)copy SMILEScopy InChI
Affinity DataIC50: 372nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50257167(CHEMBL2325619)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human NaV1.7 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21G0PQFPubMed