null
SMILES Nc1n[nH]cc1-c1cc(ccc1Oc1cc(F)c(cc1Cl)S(=O)(=O)Nc1nncs1)C(F)(F)F
InChI Key InChIKey=LRAAZMNBUIISTO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50257178
TargetCytochrome P450 3A4(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.
Curated by ChEMBL
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.
Curated by ChEMBL
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.
Curated by ChEMBL
Affinity DataIC50: 658nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of NaV1.7 ion channel (unknown origin)More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.
Curated by ChEMBL
Icagen Inc. , 4222 Emperor Blvd no. 350, Durham, North Carolina 27703, United States.
Curated by ChEMBL
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of human NaV1.5 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp metho...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human NaV1.7 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp metho...More data for this Ligand-Target Pair