null

SMILES Nc1ncnc2n(nc(-c3ccc4ccccc4c3)c12)[C@@H]1CCCN(C1)C(=O)C=C

InChI Key InChIKey=UTTWFQUHUQLZGF-GOSISDBHSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50258974   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50258974(CHEMBL4090601)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of wild type N-terminal GST-fused human EGFR cytoplasmic domain expressed in baculovirus expression system preincubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3GS9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50258974(CHEMBL4090601)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of wild type N-terminal GST-fused human EGFR cytoplasmic domain expressed in baculovirus expression system using TK-substrate after 25 min...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ358DPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50258974(CHEMBL4090601)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal GST-fused human EGFR cytoplasmic domain T790M/C797S mutant expressed in baculovirus expression system using TK-substrate aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ358DPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50258974(CHEMBL4090601)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:Inhibition of recombinant human EGFR L858R/T790M/C797S mutant using TK-substrate after 10 mins by HTRF KinEASE-TK assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ358DPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50258974(CHEMBL4090601)copy SMILEScopy InChI
Affinity DataIC50: 88nMMore data for this Ligand-Target Pair
In DepthDetails
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50258974(CHEMBL4090601)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of wild type N-terminal GST-fused human EGFR cytoplasmic domain expressed in baculovirus expression system preincubated for 30 mins follow...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3GS9PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50258974(CHEMBL4090601)copy SMILEScopy InChI
Affinity DataIC50: 88nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8XXXPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50258974(CHEMBL4090601)copy SMILEScopy InChI
Affinity DataIC50: 16nMMore data for this Ligand-Target Pair
In DepthDetails
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50258974(CHEMBL4090601)copy SMILEScopy InChI
In DepthDetails
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TU Dortmund University

Curated by ChEMBL
LigandPNGBDBM50258974(CHEMBL4090601)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant GST-tagged EGFR L858R mutant expressed in baculovirus expression system preincubated for 30 mins followed by ATP and ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3GS9PubMed