null

SMILES CCCc1ccc(cc1)C(=O)Nc1ccccc1-c1nnn(n1)-c1cccc(OC)c1

InChI Key InChIKey=JYJXKFPVGIPYGK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50261744   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY 11439, United States.

Curated by ChEMBL
LigandPNGBDBM50261744(CHEMBL4096318)copy SMILEScopy InChI
Affinity DataIC50: 131nMAssay Description:Inhibition of ABCG2 in human H460/MX20 cells assessed as potentiation of mitoxantrone induced antiproliferative activity by measuring mitoxantrone IC...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7JQ1PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY 11439, United States.

Curated by ChEMBL
LigandPNGBDBM50261744(CHEMBL4096318)copy SMILEScopy InChI
Affinity DataIC50: 207nMAssay Description:Inhibition of ABCG2 in human H460/MX20 cells assessed as potentiation of mitoxantrone induced antiproliferative activity by measuring mitoxantrone IC...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7JQ1PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY 11439, United States.

Curated by ChEMBL
LigandPNGBDBM50261744(CHEMBL4096318)copy SMILEScopy InChI
Affinity DataIC50: 131nMAssay Description:Inhibition concentration against human adenosine kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25H7JQ1PubMed