null

SMILES Cc1ccc(cc1)-c1ncc(OC[C@@H]2CCNC2)cc1-c1ccc(cc1)C#N

InChI Key InChIKey=IQVDLEXWAPYWDT-LJQANCHMSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50262048   

TargetREST corepressor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50262048(CHEMBL3134377)copy SMILEScopy InChI
Affinity DataKi:  35nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QW7PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Drug Discovery Unit, Cancer Research UK Manchester Institute, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK. Electronic address: Daniel.mould@cruk.manchester.ac.uk.

Curated by ChEMBL
LigandPNGBDBM50262048(CHEMBL3134377)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by Ionworks electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28918CTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Drug Discovery Unit, Cancer Research UK Manchester Institute, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK. Electronic address: Daniel.mould@cruk.manchester.ac.uk.

Curated by ChEMBL
LigandPNGBDBM50262048(CHEMBL3134377)copy SMILEScopy InChI
Affinity DataKd:  8nMAssay Description:Binding affinity to LSD1 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28918CTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Drug Discovery Unit, Cancer Research UK Manchester Institute, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK. Electronic address: Daniel.mould@cruk.manchester.ac.uk.

Curated by ChEMBL
LigandPNGBDBM50262048(CHEMBL3134377)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of LSD1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95DFGPubMed
TargetREST corepressor 1(Homo sapiens (Human))TBA
LigandPNGBDBM50262048(CHEMBL3134377)copy SMILEScopy InChI
Affinity DataKd:  14nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QW7PubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Drug Discovery Unit, Cancer Research UK Manchester Institute, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK. Electronic address: Daniel.mould@cruk.manchester.ac.uk.

Curated by ChEMBL
LigandPNGBDBM50262048(CHEMBL3134377)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of recombinant human N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using histone H3(1-21)K4(Me1) biotin pe...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28918CTPubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Drug Discovery Unit, Cancer Research UK Manchester Institute, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK. Electronic address: Daniel.mould@cruk.manchester.ac.uk.

Curated by ChEMBL
LigandPNGBDBM50262048(CHEMBL3134377)copy SMILEScopy InChI
Affinity DataEC50:  62nMAssay Description:Inhibition of LSD1 in human THP1 cells assessed as induction of CD11b expression after 4 days by LIVE/DEAD violet staining based FACS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95DFGPubMed